Opinion of the SCF on the Tolerable Upper Intake Level of Vitamin B1

Short Description
Animal experiments have shown that the rate of vitamin B … mostly based on the activity of enzymes with vitamin B. 1. as co-enzyme. Erythrocyte …

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Content
EUROPEAN COMMISSION
HEALTH & CONSUMER PROTECTION DIRECTORATE-GENERAL
Directorate C - Scientific Opinions
C2 - Management of scientific committees; scientific co-operation and networks
Scientific Committee on Food
SCF/CS/NUT/UPPLEV/46 Final
16 July 2001
Opinion
of the Scientific Committee on Food
on
the Tolerable Upper Intake Level of Vitamin B1
(expressed on 11 July 2001)
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http://europa.eu.int/comm/food/fs/sc/scf/index_en.htmlSCF/CS/NUT/UPPLEV/46 Final
2
Opinion of the Scientific Committee on Food on
the Tolerable Upper Intake Level of Vitamin B1
(expressed on 11 July 2001)
FOREWORD
This opinion is one in the series of opinions of the SCF on the upper levels of vitamins and
minerals. The terms of reference given by the European Commission for this task, the related
background and the guidelines used by the Committee to develop tolerable upper intake levels
for vitamins and minerals used in this opinion, which were expressed by the SCF on 19
October 2000, are available on the Internet at the pages of the SCF, at the address:
http://www.europa.eu.int/comm/food/fs/sc/scf/index_en.html.
1. INTRODUCTION
Vitamin B1 or Thiamine, formerly known as Aneurine, is 3-(4-amino-2-methylpyrimidin-5-
ylmethyl)-5-(2-hydroxyethyl)-4-methylthiazolium. The free vitamin is a base. It is isolated
and synthesized and used in food supplements and in food fortifications as a solid thiazolium
salt in the form of thiamine hydrochloride or thiamine mononitrate. The molecular weight of
thiamine hydrochloride is 337.29 g per mol. It is soluble in water and stable to heat…